问题详情

Cigarettes leave you with more than a smoky scent on your clothes and fingernails. A new study has found evidence tobacco 【M1】______ use can chemically modify and effect the activity of genes known 【M2】______ to increase the risk of developing cancer. The finding may give researchers a new tool to assessing cancer risk among people who 【M3】______ smoke. DNA isnt destiny. Chemical compounds that affect the functioning of genes can bind to our genetic material, turning certain genes on or of. These so-called epigenetic modifications 【M4】______ can influence variety of traits, such as obesity and sexual 【M5】______ preference. Scientists have even identified specific epigenetic patterns on the genes of people who smoke. None of the modified genes has a direct link to cancer, therefore, making it unclear 【M6】______ whether these chemical alterations increase the risk of developing the disease. In the new study, publishing in Human Molecular Genetics, 【M7】______ researchers analyzed epigenetic signatures in blood cells from 374 individuals enrolled in the European Prospective Investigation into Cancer and Nutrition. EPIC, which its known, is a massive 【M8】______ study aimed at linking diet, lifestyle, and environmental factors to the incident of cancer and other chronic diseases. Half of the 【M9】______ group consisted in people who went on to develop colon or breast 【M10】______ cancer 5 to 7 years after first joining the study, whereas the other half remained healthy.

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